A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation

Author(s):

Daniel Rawlinson, Chenxi Zhou, Myrsini Kaforou, Kim Anh Lê Cao, Lachlan J.M. Coin, Luregn J. Schlapbach, Sainath Raman, Natalie Sharp, Natalie Phillips, Adam Irwin, Ross Balch, Amanda Harley, Kerry Johnson, Zoe Server, Shane George, Keith Grimwood, Peter J. Snelling, Arjun Chavan, Eleanor Kitkatt, Luke Law-Ton, Allison Hempenstall, Pelista Pilot, Kristen S. Gibbons, Renate Le Marsney, Antje Blumenthal, Carolyn Pardo, Jessica Kling, Stephen McPherson, Anna D. McDonald, Seweryn Bialasiewicz, Trang Pham, Devika Ganesamoorthy, Lachlan Coin

Details:

PLOS Digital Health, Volume 4, Issue 3 March, 2025-03-01, Article number e0000780

Article Link: Click here

Affiliations:

• University of Cambridge
• University of Melbourne
• The University of Queensland
• Griffith University
• Imperial College Faculty of Medicine
• Wellcome Sanger Institute
• Kinderspital Zürich
• The Peter Doherty Institute for Infection and Immunity
• UQ Centre for Clinical Research
• Gold Coast University Hospital
• Townsville University Hospital
• Queensland Children’s Hospital
• Gold Coast Hospital and Health Service
• Thursday Island Hospital