A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-γ

Author(s):

Samantha Chan, Mai B. Margetts, Longfei Wang, Jack Godsell, Josh Chatelier, Belinda Liu, Charlotte A. Slade, Andrew Brett, Kasha P. Singh, Vanessa L. Bryant, Lauren J. Howson

Details:

Journal of Clinical Investigation, Volume 135, Issue 8, 2025-04-15, Article number e186799

Article Link: Click here

Affiliations:

• Royal Melbourne Hospital
• Walter and Eliza Hall Institute of Medical Research
• University of Melbourne
• The Peter Doherty Institute for Infection and Immunity
• Austin Health