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Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery


Author(s):

Amanda X.Y. Chen, Kah Min Yap, Joelle S. Kim, Kevin Sek, Yu Kuan Huang, Phoebe A. Dunbar, Volker Wiebking, Jesse D. Armitage, Isabelle Munoz, Kirsten L. Todd, Emily B. Derrick, Dat Nguyen, Junming Tong, Cheok Weng Chan, Thang X. Hoang, Katherine M. Audsley, Marit J. van Elsas, Jim Middelburg, Joel N. Lee, Maria N. de Menezes, Thomas J. Cole, Jasmine Li, Christina Scheffler, Andrew M. Scott, Laura K. Mackay, Jason Waithman, Jane Oliaro, Simon J. Harrison, Ian A. Parish, Junyun Lai, Matthew H. Porteus, Imran G. House, Phillip K. Darcy, Paul A. Beavis

Details:

Nature, Volume 644, Issue 8075, 2025-08-07

Article Link: Click here

Affiliations:

  • Stanford University
  • University of Melbourne
  • Monash University
  • The University of Western Australia
  • Peter Maccallum Cancer Centre
  • The Kids Research Institute Australia
  • Faculty of Medicine, Dentistry and Health Sciences
  • The Peter Doherty Institute for Infection and Immunity
  • Olivia Newton-John Cancer Research Institute

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