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Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies


Author(s):

Julia Lederhofer, Andrew J. Borst, Lam Nguyen, Rebecca A. Gillespie, Connor J. Williams, Emma L. Walker, Julie E. Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon Xhi Tan, Thi H.T. Do, Michelle Ravichandran, Adrian B. McDermott, Valerie Le Sage, Sarah F. Andrews, Barney S. Graham, Adam K. Wheatley, Douglas S. Reed, Neil P. King, Masaru Kanekiyo

Details:

Nature Communications, Volume 16, Issue 1, 2025-12-01, Article number 7068

Article Link: Click here

Affiliations:

  • University of Washington
  • University of Pittsburgh School of Medicine
  • University of Washington School of Medicine
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • The Peter Doherty Institute for Infection and Immunity

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