Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection

Author(s):

Stefanie M. Bader, Lena Scherer, Reet Bhandari, Allan J. Motyer, James P. Cooney, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, David V. L. Romero, Jan Schaefer, Jiyi Pang, Siqi Chen, Kael Schoffer, Le Wang, Xinyi Jin, Daniel Batey, Raymond K.H. Yip, Ishrat Zaman, Pradeep Rajasekhar, Matthew J. Gartner, Stephen Wilcox, Lachlan Whitehead, Smitha Rose Georgy, Ana Maluenda, Kathryn C. Davidson, Cody C. Allison, Rory Bowden, Kerstin Brinkmann, Marie Liesse Asselin-Labat, Belinda Phipson, Maria C. Tanzer, Marco J. Herold, Andre L. Samson, James E. Vince, Andreas Strasser, Marc Pellegrini, Marcel Doerflinger

Details:

Nature Communications, Volume 16, Issue 1, 2025-12-01, Article number 9822

Article Link: Click here

Affiliations:

• University of Melbourne
• Nankai University
• University of Technology Sydney
• Walter and Eliza Hall Institute of Medical Research
• Department of Microbiology & Immunology
• Olivia Newton-John Cancer Research Institute
• Faculty of Science