Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes

Author(s):

Junyun Lai, Cheok Weng Chan, Jesse D. Armitage, Katherine M. Audsley, Yu Kuan Huang, Emily B. Derrick, Laura S. Carstensen, Christina M. Scheffler, Matt E. Jones, Kevin Sek, Nicola Principe, Joelle S. Kim, Imran G. House, Amanda X.Y. Chen, Kah Min Yap, Jim Middelburg, Isabelle Munoz, Dat Nguyen, Junming Tong, Thang X. Hoang, Kirsten L. Todd, Maximilien Evrard, Jonathan Chee, Laura K. Mackay, Alistair R.R. Forrest, Ian A. Parish, Anthony Bosco, Jason Waithman, Paul A. Beavis, Phillip K. Darcy

Details:

Nature Immunology, Volume 27, Issue 3, 2026-03-01

Article Link: Click here

Affiliations:

• University of Melbourne
• Monash University
• The University of Western Australia
• University of Arizona College of Medicine – Tucson
• The University of Arizona Health Sciences
• Peter Maccallum Cancer Centre
• The Kids Research Institute Australia
• Department of Microbiology & Immunology
• The Harry Perkins Institute of Medical Research