Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18–55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial

Author(s):

Keith J. Chappell, Francesca L. Mordant, Alberto A. Amarilla, Naphak Modhiran, Benjamin Liang, Zheyi Li, Julia A. Lackenby, Noushin Jaberolansar, Jake O’Donnell, Vivian Kienzle, Varsha Kommajosyula, Nicolas Tardiota, Jillian K. Bennet, Christina L. Henderson, Rhiannon L. Dalrymple, Justin Goh, Kym Hoger, Marianne Gillard, Martina L. Jones, Karen Hughes, Ben Hughes, James Barnes, Patrick C. Reading, Charani Ranasinghe, Kanta Subbarao, Trent P. Munro, Paul R. Young, Daniel Watterson

Details:

Journal of Infectious Diseases, Volume 233, Issue 2, 2026-02-15

Article Link: Click here

Affiliations:

• The University of Queensland
• The John Curtin School of Medical Research
• Department of Microbiology & Immunology
• The Peter Doherty Institute for Infection and Immunity
• Independent Consultant