In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice

Author(s):

Troy C. Sutton, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Wouter Koudstaal, Muniza Rehman, Gerrit Jan Weverling, Jaap Goudsmit, Kanta Subbarao

Details:

Journal of Virology, Volume 91, Issue 24, 2017-12-01, Article number e01603-17

Article Link: Click here

Affiliations:

• Harvard T.H. Chan School of Public Health
• National Institute of Allergy and Infectious Diseases (NIAID)
• Huck Institutes of the Life Sciences
• World Health Organization, Australia
• Janssen Vaccines & Prevention B.V.