Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. Falciparum Humanized NOD-scid IL2Rnull Mouse Model of Malaria

Author(s):

Paul R. Gilson, William Nguyen, William A. Poole, Jose E. Teixeira, Jennifer K. Thompson, Kaiyuan Guo, Rebecca J. Stewart, Trent D. Ashton, Karen L. White, Laura M. Sanz, Francisco Javier Gamo, Susan A. Charman, Sergio Wittlin, James Duffy, Christopher J. Tonkin, Wai Hong Tham, Brendan S. Crabb, Brian M. Cooke, Christopher D. Huston, Alan F. Cowman, Brad E. Sleebs

Details:

Antimicrobial Agents and Chemotherapy, Volume 63, Issue 3, 2019-03-01, Article number e01804-18

Article Link: Click here

Affiliations:

• University of Melbourne
• Monash University
• Universität Basel
• The University of Vermont
• University of Vermont Larner College of Medicine
• Walter and Eliza Hall Institute of Medical Research
• Swiss Tropical and Public Health Institute Swiss TPH
• Department of Microbiology & Immunology
• Burnet Institute
• GlaxoSmithKline plc, Spain
• ICC