Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d -Phe-6, and the N-Terminus Enabled by S-Lipidation

Author(s):

Paul W.R. Harris, Andrew Siow, Sung Hyun Yang, Andrew D. Wadsworth, Lyndia Tan, Yann Hermant, Yubing Mao, Chalice An, Cameron C. Hanna, Alan J. Cameron, Jane R. Allison, Aparajita Chakraborty, Scott A. Ferguson, Sonya Mros, Kiel Hards, Gregory M. Cook, Deborah A. Williamson, Glen P. Carter, Susanna T.S. Chan, Gavin A. Painter, Veronika Sander, Alan J. Davidson, Margaret A. Brimble

Details:

ACS Infectious Diseases, Volume 8, Issue 12, 2022-12-09

Article Link: Click here

Affiliations:

• The University of Auckland
• The Peter Doherty Institute for Infection and Immunity
• School of Biological Sciences
• University of Otago
• Victoria University of Wellington