SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates
Author(s):
Stefanie M. Bader, James P. Cooney, Dylan Sheerin, George Taiaroa, Leigh Harty, Kathryn C. Davidson, Liana Mackiewicz, Merle Dayton, Stephen Wilcox, Lachlan Whitehead, Kelly L. Rogers, Smitha Rose Georgy, Anna K. Coussens, Samantha L. Grimley, Vincent Corbin, Miranda Pitt, Lachlan Coin, Raelene Pickering, Merlin Thomas, Cody C. Allison, Julie McAuley, Damian F.J. Purcell, Marcel Doerflinger, Marc Pellegrini
Details:
Proceedings of the National Academy of Sciences of the United States of America, Volume 120, Issue 32, 2023-08-08, Article number e2301689120
Article Link: Click here
Affiliations:
- Faculty of Science
- The Peter Doherty Institute for Infection and Immunity
- Walter and Eliza Hall Institute of Medical Research
- University of Melbourne
- Monash University
- Royal Melbourne Hospital