Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model

Author(s):

Jinchao Hou, Yun Chen, Zhangying Cai, Gyu Seong Heo, Carla M. Yuede, Zuoxu Wang, Kent Lin, Fareeha Saadi, Tihana Trsan, Aivi T. Nguyen, Eleni Constantopoulos, Rachel A. Larsen, Yiyang Zhu, Nicole D. Wagner, Nolan McLaughlin, Xinyi Cynthia Kuang, Alexander D. Barrow, Dian Li, Yingyue Zhou, Shoutang Wang, Susan Gilfillan, Michael L. Gross, Simone Brioschi, Yongjian Liu, David M. Holtzman, Marco Colonna

Details:

Science Translational Medicine, Volume 16, Issue 741, 2024-01-01, Article number eadj9052

Article Link: Click here

Affiliations:

• Washington University School of Medicine in St. Louis
• The Peter Doherty Institute for Infection and Immunity
• The University of Hong Kong Li Ka Shing Faculty of Medicine
• Washington University in St. Louis
• Mallinckrodt Institute of Radiology
• Mayo Clinic