SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years

Author(s):

Louise C. Rowntree, Jennifer Audsley, Lilith F. Allen, Hayley A. McQuilten, Ruth R. Hagen, Priyanka Chaurasia, Jan Petersen, Dene R. Littler, Hyon Xhi Tan, Lydia Murdiyarso, Jennifer R. Habel, Isabelle J.H. Foo, Wuji Zhang, Elizabeth R.V. ten Berge, Hanujah Ganesh, Prathanporn Kaewpreedee, Kelly W.K. Lee, Samuel M.S. Cheng, Janette S.Y. Kwok, Dhilshan Jayasinghe, Stephanie Gras, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Jamie Rossjohn, Allen C. Cheng, Tom C. Kotsimbos, Jason A. Trubiano, Natasha E. Holmes, Ken Ka Pang Chan, David S.C. Hui, Malik Peiris, Leo L.M. Poon, Sharon R. Lewin, Peter C. Doherty, Irani Thevarajan, Sophie A. Valkenburg, Katherine Kedzierska, Thi H.O. Nguyen

Details:

Proceedings of the National Academy of Sciences of the United States of America, Volume 121, Issue 39, 2024-09-24, Article number e2411428121

Article Link: Click here

Affiliations:

• Monash University
• University of Melbourne
• The Peter Doherty Institute for Infection and Immunity
• Peter Maccallum Cancer Centre
• La Trobe University
• Cardiff University School of Medicine
• HKU-Pasteur Research Pole
• The University of Hong Kong Li Ka Shing Faculty of Medicine
• Chinese University of Hong Kong, Faculty of Medicine
• Queen Mary Hospital Hong Kong
• Prince of Wales Hospital Hong Kong
• The Alfred
• Royal Melbourne Hospital
• Austin Health
• Centre for Immunology and Infection