Influenza A(H5N1) viruses with A(H9N2) single gene (matrix or PB1) reassortment isolated from Cambodian live bird markets

Authors:

• Suttie, Annika
• Karlsson, Erik A.
• Deng, Yi-Mo
• Horm, Srey Viseth
• Yann, Sokhoun
• Tok, Songha
• Sorn, San
• Holl, Davun
• Tum, Sothyra
• Hurt, Aeron C.
• Greenhill, Andrew R.
• Barr, Ian G.
• Horwood, Paul F.
• Dussart, Philippe

Details:

Virology, Volume 523, 2018-10-31

Article Link: Click here

Live bird market surveillance for avian influenza viruses in Cambodia in 2015 has led to the detection of two 7:1 reassortant influenza A(H5N1) clade 2.3.2.1c viruses. These reassortant strains, designated A/duck/Cambodia/Z564W35M1/2015 and A/chicken/Cambodia/Z850W49M1/2015, both contained a single gene (PB1 and matrix gene, respectively) from concurrently circulating A(H9N2) influenza viruses. All other viral genes from both isolates clustered with A(H5N1) clade 2.3.2.1 viruses. Continued and prolonged co-circulation of influenza A(H5N1) and A(H9N2) viruses in Cambodian live bird markets may present a risk for the emergence of novel influenza reassortant viruses with negative agricultural and/or public health implications.