ICOS-play: dressing T cells for residency

Authors:

• Park, Simone L.
• Christo, Susan N.
• Mackay, Laura K.

Details:

Trends in Immunology, Volume 43, Issue 4, 2022-04-30

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Efficient generation of tissue-resident memory T (TRM) cells is essential for long-lived immune protection in barrier tissues. Peng et al . now show that the costimulatory molecule ICOS enhances CD8+ TRM cell lodgment by promoting early tissue retention.