Immunological imprinting: Understanding COVID-19

Authors:

• Koutsakos, Marios
• Ellebedy, Ali H.

Details:

Immunity, Volume 56, Issue 5, 2023-05-09

Article Link: Click here

Immunological imprinting generically refers to the effects prior exposures have on subsequent immune responses to, and eventually protection against, antigenically related viruses. Here, Koutsakos and Ellebedy explain different concepts and terms around imprinting and the fundamental immunological principles behind it. They also discuss the potential role imprinting may have in the context of COVID-19 vaccines.