SWI/SNF chromatin remodeling complexes as key regulators of CD8+ T cell fate

Authors:

• Rausch, Lisa
• Kallies, Axel

Details:

Immunity, Volume 56, Issue 6, 2023-06-13

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CD8+ T cell fate is tightly regulated by epigenetic modification. In this issue of Immunity, McDonald et al. and Baxter et al. demonstrate that the chromatin remodeling complexes cBAF and PBAF control proliferation, differentiation, and function of cytotoxic T cells in response to infection as well as cancer.