Strength in diversity: Widening B cell recruitment for broader vaccine protection

Authors:

• Wheatley, Adam K.
• Kent, Stephen J.

Details:

Immunity, Volume 56, Issue 10, 2023-10-10

Article Link: Click here

Generating potent neutralizing antibodies is a unifying goal of next-generation vaccines. In this issue of Immunity, Ols et al. show that multivalent nanoparticle vaccines displaying RSV F protein can enable recruitment of more diverse B cell specificities into the vaccine response, resulting in increased potency and breadth of antibody immunity to both RSV and the related human metapneumovirus.