The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: A new transcription factor for lymph node homeostasis

Mueller Group

Lymph nodes are critical for immune responses. Within lymph nodes, specialised fibroblasts construct and support the tissue by defining distinct compartments and providing signals that can either promote or inhibit immune responses. We recently identified a new transcription factor required that support the differentiation and homeostatic functions of these fibroblasts, and regulate antiviral T cell responses. This project will investigate how this novel transcription factor regulates lymph node homeostasis and the initiation of immune responses to infection. For this, we will use a use a new animal model, flow cytometry and confocal imaging.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Professor Scott Mueller

Project Co-supervisor

Dr Yannick Andre

Project availability
Master of Biomedical Science

Mueller Group

6 vacancies

Viral Infectious Diseases
Cross Cutting Disciplines
Discovery Research

Research in the Mueller group is focused on examining immune responses to acute and chronic viral infections and to tumours. We are using state-of-the-art methods, including intravital 2-photon microscopy, to visualise immune cells and pathogens in real time.

Mueller Group Current Projects