Project: Microbial changes following pneumococcal conjugate vaccination
Pneumococci are a major global pathogen. Pneumococcal conjugate vaccines (PCVs) protect against a subset of pneumococcal serotypes. Introduction of PCVs result in major changes to pneumococcal epidemiology and to the microbiota more broadly. In this project, you will examine nasopharyngeal samples and isolates collected from children from vaccine studies in low-income settings from the Asia-Pacific region. You will apply traditional and molecular microbiology approaches including culture and serotyping, qPCR, DNA microarray, whole-genome sequencing and antimicrobial resistance testing. Your results will inform vaccine strategies world-wide.
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The Satzke group conducts research in a clinically-relevant context. We focus on the microbiology of pathogens of major global health importance (including pneumococcus and group A streptococcus) to understand their pathogenesis, interaction with viruses, and how infections can be best prevented with vaccines.
Satzke Group Current Projects
Understanding pneumococcal pathogenesis
PhD/MPhil, Master of Biomedical Science, Honours
Microbial changes following pneumococcal conjugate vaccination
Master of Biomedical Science, Honours