10 May 2021
Setting it Straight: Vaccination and some basic considerations re Interventional Clinical Trials
Anyone who was keeping a close watch on unfolding events through 2020 as the various COVID-19 vaccine candidates (#43, #44) were being tested in humans would be familiar with the idea that the evaluation process requires a progression through ‘graded’ Phase I, Phase 2 and Phase 3 clinical trials. What was so fascinating here was to watch the rapidly emerging stature of novel products (the candidates) as ‘interventions’ to lessen the risk posed to humans by SARS-CoV-2 infection. So far as I’m aware, the ‘intervention’ with all the COVID-19 vaccines tested so far has been to inject 0.5ml or more of fluid containing the candidate vaccine deep into the musculature (the deltoid) of the upper arm (#40).