Clinical and health systems research |Clinical Trials

Antiretroviral therapy (ART) prevents HIV related morbidity but HIV cannot be cured due to persistence of infected CD4+ T-cells that reactivate when ART is ceased.  Tissue sites such as lymph nodes and the gut are important sites for HIV persistence on ART but require surgery or biopsies to assess residual infection.  An imaging method to detect HIV infected T-cells would allow for a non-invasive method to accurately quantify where HIV persists on ART.  This tool would have a major impact on understanding where and how virus persists on ART and strategies to eliminate HIV persistence.

This study is now closed to recruitment.

Coordinating Principal Investigator

Dr James McMahon (Alfred Hospital)
+61 3 9076 6908
james.mcmahon@monash.edu

Principal Investigator (Doherty)

Prof Sharon Lewin
+61 3 8344 3159
sharon.lewin@unimelb.edu.au