Host cell kinome project
This project aims to investigate new treatments for COVID-19 by targeting human hosts, rather than the pathogen itself. This study will identify host cell kinases modulated by SARS-CoV-2 infection, to identify antiviral compounds that specifically inhibit SARS-CoV-2 - host factor interactions, which are essential for virus replication. This approach has proven successful for other human pathogens including malaria, dengue and hepatitis C virus and will make an important contribution to efforts to respond to the COVID-19 pandemic.
