Project: Breaking bacterial antibiotic resistance using ionobiotics
McDevitt group
Antibiotic-resistant pathogens represent an imminent global threat to health in the 21st century. The combination of rising rates of bacterial drug resistance and a waning antibiotic development pipeline requires that new approaches be developed to address this imminent healthcare crisis. This project will investigate the use of novel metal ion shuttling compounds (ionobiotics) to break drug resistance in high priority bacterial pathogens and render them susceptible to antibiotic treatment. This approach has the potential to restore the efficacy of our existing antibiotic arsenal.
Contact project supervisor for further
information and application enquiries
McDevitt group
4 vacancies
Research in the McDevitt group seeks to understand how bacterial pathogens acquire and use metal ions and how this shapes the host-pathogen interaction during infection.
McDevitt group Current Projects
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Defining the metal ion homeostatic pathways of Klebsiella pneumoniae
PhD/MPhil, Honours
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Breaking bacterial antibiotic resistance using ionobiotics
PhD/MPhil, Master of Biomedical Science, Honours
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Bacterial subversion strategies to resist host-mediated copper stress
PhD/MPhil, Honours
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Targeting Klebsiella pneumoniae virulence by exploiting weaknesses in metal ion homeostasis
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.