The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Investigating antimalarial drug resistance in response to community interventions

Day Group

Plasmodium falciparum resistance to antimalarials including chloroquine, sulphadoxine-pyrimethamine, and artemisinin-based combination therapies threatens malaria control efforts, particularly in sub-Saharan Africa where >90% of malaria-related deaths occur annually. Currently, we are monitoring the efficacy of a community-based intervention known as seasonal malaria chemoprevention, a form of targeted mass drug administration in children under 5-years, in Bongo District in the Upper East Region of Ghana in West Africa. Changes in patterns of molecular markers of antimalarial drug resistance are being monitored and analysed by genetic epidemiology methods to inform the National Malaria Control Program in Ghana, as well as to better understand the population genetics of drug resistance in the reservoir of chronic infections. 

Project site: Bio21 Institute

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information and application enquiries

Project Supervisor

Professor Karen Day

Project availability
Master of Biomedical Science

Day Group

8 vacancies

Bacterial and Parasitic Infections
Cross Cutting Disciplines
Computational Science and Genomics
Global Health
Public Health

Professor Karen Day runs a multidisciplinary malaria research group that utilises molecular epidemiology to study the role that variation in human, parasite, and vector genomes plays in modulating transmission dynamics of Plasmodium spp. She is also interested in cell-to-cell communication in malaria parasites to alter population behaviour. She has a strong track record in interdisciplinary training of the next generation of infectious disease epidemiologists.