The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Our Work | COVID-19

Antivirals and Virology

Testing SARS-CoV-2 vaccine and therapeutics using human respiratory epithelium and organoid models

There is pressing urgency to develop vaccines and therapies to treat patients with COVID-19. This project will enable the production and utilisation of tissue-restricted stem-cell derived organoids to further our understanding of SARS-CoV-2 and the biological basis for infection. Using the natural cell host (human nasal epithelium) to test binding and vaccine-elicited neutralising antibodies will advance progress towards clinical trials. Similarly, using the nasal epithelial models will fast track the efficacy of COVID-19 therapeutics.

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