The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

  • Research Groups

    Current Projects

    • Collaborations outside the Doherty Institute

      We collaborate widely with research groups in the Parkville precinct and beyond, including the Murdoch Children’s Research Institute (Melbourne), Menzies School of Health Research (Darwin), and the Telethon Kids Institute (Perth). With all of these partners we are engaged in a program of clinical, laboratory and public health research to inform healthy skin programs in remote Northern Australian communities. This work aligns with international collaborative efforts to reduce throat, skin infections and invasive bacterial infections due to Group A Streptococcus (Strep A), with associated sequelae of rheumatic fever and rheumatic heart disease.

    • Epidemiology projects

      Core activities include contributions to State and Commonwealth Department of Health funded programs of research on influenza, undertaken within the WHO Collaborating Centre for Reference and Research on Influenza. We are engaged in responsive research partnerships with the Victorian Department of Health and Human Services (DHHS) to investigate drivers of seasonal epidemic diseases such as Ross River Virus and other arboviruses; and recent changes in the geographic distribution of Buruli ulcer. These latter projects are informed by an interdisciplinary ‘One Health’ approach that recognises the importance of understanding interactions between humans, animals and the environment.

    • Work with Centres of Research Excellence (CREs)

      We are leaders and partners in nationally distributed Centres of Research Excellence funded by the NHMRC, including the Australian Partnership for Preparedness Research on Infectious Diseases Emergencies (APPRISE), the Australian Centre for Research Excellence in Malaria Elimination (ACREME), and Policy Relevant Infectious Disease Simulation and Mathematical Modelling (PRISM2). These Centres engage closely with the Sydney led Centre of Research Excellence in Emerging Infectious Diseases (CREID) and the Darwin based consortium focused on Improving Health Outcomes in the Tropical North (Hot North


    Lab Team


    • Centre for Antibiotic Allergy and Research

      The Centre for Antibiotic Allergy and Research focuses on translational drug allergy diagnostics, health services interventions and antibiotic allergy clinical trials.

      Other work areas include:Public Health


    • Howden Group

      Research from Professor Ben Howden’s group research uses genomics, molecular biology, epidemiology and clinical studies to address a broad range of issues related to invasive bacterial diseases in humans, especially those caused by staphylococci, enterococci and other antimicrobial-resistant species. Additionally, working closely with scientists in the MDU PHL, they investigate the epidemiology, evolution, and spread of bacterial pathogens of public health significance such as Neisseria gonorrhoea, Listeria monocytogenes, Shigella and Salmonella spp., Legionella spp., and carbapenemase-producing gram-negative bacteria.


    • National Centre for Antimicrobial Stewardship

      The National Centre for Antimicrobial Stewardship (NCAS) is a health services research program that aims to improve the use of antimicrobials across animal and human health, to influence national policy, and to generate a research workforce across nurses, pharmacists, doctors and veterinarians. NCAS aims to lead and facilitate the embedding of antimicrobial stewardship (AMS) within clinical practice across diverse healthcare settings and among different practitioner groups in Australia. Its research and surveillance programs aim to improve antimicrobial prescribing by understanding prescribing behaviours through qualitative and quantitative methods, monitoring current prescribing patterns across healthcare settings, identifying targets for quality improvement, and developing interventions, new policies and practices.


    • Robins-Browne Group

      Research in Roy’s laboratory is partly focused on how E. coli causes diarrhoea, with the aims of identifying better ways to diagnose, treat and prevent these infections. Another theme is the development of new types of antibacterial agents.

      Other work areas include:Enteric infections, Immunology


    • Stinear Group

      Tim Stinear’s group’s research addresses priorities across four connected themes that including hospital superbugs, pathogenic mycobacteria, natural product discovery and public health genomics that aim to understand and contain the spread of bacteria causing serious human disease. 


    • Tong Group

      Steve’s group conducts clinical trials to optimise the treatment of infections due to methicillin-resistant Staphylococcus aureus and other bacterial pathogens. He also investigates the epidemiology and genomics of streptococcal infections, hepatitis B, influenza, and antimicrobial resistance in Australian Indigenous communities.

      Other work areas include:Staphylococcus aureus, Immunology, Viral Infectious Diseases, Bacterial and Parasitic Infections, Public Health


    • VICNISS

      The VICNISS Coordinating Centre provides a state-wide, standardised surveillance service for healthcare associated infections (HAIs) and related events. The goal of VICNISS is to monitor and reduce the incidence of HAIs, providing support for health services in Victoria. VICNISS aims to support Victorian health services to carry out international best practice surveillance and analysis, and to lead interventions for quality improvement to improve the health of all Victorians.

      VICNISS provides a source of high quality data for regular performance monitoring, and for a valuable resource for the research community. Over the time of VICNISS surveillance, infection rates in key areas of focus have fallen markedly, reducing the significant financial and personal cost of these infections on both individual patients and the health system.

      VICNISS collaborates with the National Centre for Antimicrobial Stewardship (NCAS), with a major involvement in aged care NAPS (ac-NAPS). VICNISS is also engaged by DHHS Residential Aged Care Services to carry out monitoring of infection control indicators in Victoria’s public residential aged care services, including participation in ac-NAPS.