The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Dr Celine Gubser

Dr Celine Gubser

(03) 9035 7912 | celine.gubser@unimelb.edu.au

Position:
Post-doctoral Research Fellow
Theme(s):
Immunology, Viral Infectious Diseases, Bacterial and Parasitic Infections
Discipline(s):
Discovery Research, Clinical and health systems research
Unit(s):
The University of Melbourne, Department of Microbiology and Immunology (DMI) , Department of Infectious Diseases
Lab Group(s):
Lewin Group

Dr Celine Gubser is a postdoctoral researcher in the Immunomodulation group within the laboratory of Professor Sharon Lewin. Her work focuses on novel immune modulating agents and their ability to boost HIV directed immune responses and eliminate latently infected cells. Celine accomplished her medical studies in 2011 and obtained her PhD at the University of Basel, Switzerland, in 2015 where she studied the suppressive mechanisms of regulatory T cells and T cell tolerance under Professor Ed Palmer. There after she did a 2-year assignment as registrar in internal medicine at the University hospital Basel.

  • Key Achievements
    • Celine was awarded a Novartis research fellowship in 2018 to undertake her postdoctoral studies in HIV cure research. Her PhD work helped understand the molecular mechanism underlaying the affinity threshold for negative selection.* She further studied how peripheral tolerance is maintained by regulatory T cells showing that the strength of TCR stimulation determined the efficacy of regulatory T cell mediated suppression.

      *Osswald, C (maiden name)

    Research Groups
    • Lewin Group

      The focus of the Lewin group is to understand why HIV infection persists on antiretroviral therapy and to develop new strategies to eliminate latency. The lab also researches factors that drive liver disease in HIV-hepatitis B virus co-infection. The lab is also actively involved in COVID in relation to pathogenesis, the use of primary tissue models, and developing therapeutics using gene editing strategies.


      Lab Team

      Lewin Group

      • Director - The Peter Doherty Institute for Infection and Immunity
      • Senior Research Fellow
      • Senior Research Fellow
      • Dr Wei Zhao
        Research Fellow
      • Dr Chris Chiu
        Research Fellow
      • Dr Youry Kim
        Research Fellow
      • Dr Stan Kan
        Research Fellow
      • Dr Jill Lau
        Clinical Research Fellow
      • Clinical Research Liason Officer
      • Dr Judy Chang
        Research Systems Administrator
      • Dr Catherine Kennedy
        Research Coordinator
      • Research Coordinator
      • Laboratory Manager
      • Infectious Diseases Physician
      • Carolin Tumpach
        Research Support Officer
      • Rosalyn Cao
        Research Support Officer
      • Danielle Fong
        Research Support Officer
      • Abigail Tan
        Research Support Officer
      • Jared Stern
        PhD Candidate
      • Rachel Pascoe
        PhD Candidate
      • Paula Cevaal
        PhD Candidate
      • Haoming Liu
        PhD Candidate
      • Kiho Tanaka
        PhD Candidate
      • Rory Shepherd
        PhD Candidate
      • Lauren Wallace
        Honours Student
      • Bridget Fisher
        Honours Student
      • Associate Professor Edwina Wright
        Clinical Affiliate
      • Dr James McMahon
        Clinical Affiliate
      • Head, Clinical Virology and HIV Services, Deputy Director Department of Infectious Diseases Austin Health
      • Associate Professor Thomas Rasmussen
        Clinical Affiliate