Sarah’s group is using host and pathogen genomics to better understand infectious diseases. They perform genome-wide association studies of the host, genomic studies of the pathogen, and investigate the interaction of both genomes in tuberculosis, enteric fever and malaria patients.
Other work areas include:Enteric infections, Malaria
Victorian Tuberculosis Program Group
Justin’s group specialises tuberculosis (TB) with an emphasis on latent TB and conducts activities ranging from expansion of theoretical foundations for understanding latency and risk associated with TB infection to socio-cultural engagement with communities at high risk for TB, and development of strategic public health policies towards TB elimination. The group includes researchers with expertise in a range of methodologies, including clinical research, epidemiology, mathematical modelling, ethics and interventional research.
Researchers at the Doherty Institute are engaged in broad clinical research efforts related to tuberculosis (TB) disease, management and elimination. There is an active program of population health and mathematical modelling research assisting with evaluation of effective and ethical TB strategies both in Australia and internationally. In parallel, basic research on TB includes understanding the TB genome and the body’s immune response to TB. These activities are strengthened by a range of state-wide services for public health management of TB provided at the Doherty Institute including clinical care, epidemiology, contact tracing and rapid diagnosis of infection and drug resistance. The close collaboration amongst groups with complementary expertise means that the Doherty Institute is an exciting environment for developing and implementing novel, high-impact strategies towards better TB care and global elimination of this disease.
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The interaction between the host and pathogen genetics in susceptibility to tuberculosis
The role of unconventional T cells in cancer immunity
developed TB in 2014