Dr Hoanh Tran
+61 (0) 3 8344 5773 | hoanh.tran@unimelb.edu.au
- Position:
- Joint Laboratory Head, Senior Research Fellow
- Theme(s):
- Immunology, Viral Infectious Diseases, Bacterial and Parasitic Infections
- Discipline(s):
- Discovery Research, Clinical and health systems research
- Unit(s):
- Department of Infectious Diseases, Victorian Infectious Diseases Reference Laboratory (VIDRL)
- Lab Group(s):
- Vincan Group
Dr Hoanh Tran earned his BSc (Hons) from the University of Melbourne and a PhD in Cell Biology from the Friedrich Miescher Institute in Switzerland studying mRNA stability. He conducted postdoctoral research at the MRC Laboratory of Molecular Biology in the UK and Genentech in the USA, where he studied how the ubiquitin system regulates the tumour suppressor functions of the adenomatous polyposis coli (APC) protein. He is now using knowledge from the discovery of new ubiquitin-APC biology to further research into the mechanisms of Wnt signalling, cell growth, and tissue morphogenesis in human health and disease.
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Key Achievements
Publications
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Dr Tran has studied signalling pathways regulating cell growth and survival for over 15 years at leading scientific institutions in Europe, the USA, and Australia. At WEHI in Melbourne, he led projects investigating the genetic and metabolic requirements for cell survival, and identified a novel ubiquitin-dependent pathway driving axon growth and guidance. In 2022, Dr Tran was appointed joint Laboratory Head in Prof Elizabeth Vincan’s group at the Doherty Institute, where he will continue to study new Wnt and ubiquitin signalling mechanisms in human health and disease.
Research GroupsLoading ORCID data…-
Vincan Group
Elizabeth’s group investigates novel ways to block cancer growth with a focus on the gastrointestinal tract – stomach, bowel and liver. A cell-cell communication pathway called Wnt is hyperactive in these cancers. Their research shows inhibiting Wnt has potent anti-cancer effects.
Lab Team
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Medical Scientist / Laboratory Head
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Research Fellow
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Joint Laboratory Head, Senior Research Fellow
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Jean MoselenResearch Fellow
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Dr Sarah HarbachResearch Fellow/Medical Scientist
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Dr George KastrappisResearch Fellow/Medical Scientist
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